Mutation library

Curated, clinically actionable kinase mutations you can dock against in one click — wild-type versus mutant, side by side. Each entry ships with a validated structure and a ready-to-run setup.

Covered targets include EGFR (T790M, C797S, exon-19 deletions), BCR-ABL (T315I), BRAF (V600E), KRAS (G12C, G12D), and ALK (G1202R). Free for academic use, no install. Open Studio or read the mutation docking guide.